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Rival drugmakers remain in talks about potential deal following latest rebuff

Amount prescribed dropped 12% last year as moves to curb addiction crisis bore fruit

Deal will increase P&G’s presence in biggest over-the-counter healthcare markets

Interview World

New president wants to create ‘conducive investment climate’ after years of scandal

Analysis Industrials

First-quarter earnings will show how much progress chief is making

The coder on the highs and lows of being at the helm of one of the most successful cryptocurrencies

Beijing delays $44bn takeover with demand for better remedies on competition

Expectations of three or even four hikes this year rise as growth worries persist

Matt Zames will oversee all financial service sector deals at US buyout firm

Filing shows cable group was not offering a payment if deal collapsed

IMF urges more taxes to help pay interest that has hit levels not seen for 18 years

US News

Attorneys-general redress Trump administration’s scaling back of federal regulator

US streaming service will double production budget in region in 2018

Volatility index jumped in the moments before derivatives contracts were priced

Pressure on social media group over data handling drives belated step into growing area

Opinion

Highlights

Thirty years ago, Helen Barrett hoped for a revolution. Could it finally be here?

Robots, sun shields and ‘coral IVF’ used to tackle impact of climate change

The Instagram star on how self-esteem is at the heart of her brand

Markets News

Crude-linked currencies also rally as investors eye longer production curbs

Three-month correlation of stocks in the S&P 500 index has rocketed to 52%

Russia produces over more than 10% of the world’s nickel and 40% of palladium

Technology

Beijing delays $44bn takeover with demand for better remedies on competition

Inside Business Richard Waters

Regulatory risks will not stop big tech race to give world its first $1tn company

Move against Telegram app wreaks wider havoc — perhaps on purpose

Life & Arts