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Combating Tuberculosis

Inside this issue

• Discoveries about basic TB biology are guiding researchers

• Frontline workers have untapped knowledge relevant to everything from clinic design to treatment - -

Content

Fight needs money and leadership

Financial austerity is a broad threat to progress, with cuts in healthcare budgets and international donor support, writes Andrew Jack

Drug supply: Business retreats from unattractive market

Orders are fragmented and there is pressure to price products as cheaply as possible, notes Andrew Jack

Patient care: Nurses are underused and undervalued

Frontline workers have untapped knowledge relevant to everything from clinic design to treatment, says Sarah Murray

New medicines: Knowledge of the enemy will widen our armoury

Recent discoveries about the basic biology of TB should help to improve treatment, writes Clive Cookson

Diagnostics: Molecular test offers hope for detecting drug resistance

The WHO has endorsed ‘Xpert’ but the machines are expensive, says Charis Gresser

Treatment: Surgery can help in some difficult cases

Russia has always been wedded to an approach that can be useful against resistant strains, writes Andrew Jack

Romania: ‘The future looks really dark’

Global Fund money runs out next year, notes Andrew Jack

India: Rural healers can help with treatment

The country has made big strides in improving diagnosis and treatment, writes Amy Kazmin

New vaccines: A financial booster

Scientists are rapidly coming up with new vaccine candidates to supplement and then replace BCG, writes Clive Cookson

Case study: Eradication becomes harder as cases dwindle

Now the disease is rarer, fewer doctors can diagnose it, says Alan Rappeport

Case study: UK – an exercise in persuasion

Guest column: Emerging global leaders should take a stand

Guest Column: Nurses must be at the heart of developing patient-centred care