Ratification of the European Union’s reform treaty could be made more difficult by the fall of the Czech government and its knock-on effect for the EU presidency, which is held by Prague, officials warned on Wednesday.

In Strasbourg, Alexandr Vondra, Czech deputy prime minister, said Prague’s ratification of the Lisbon treaty, which requires the approval of all 27 countries in the EU bloc, could be more problematic after Tuesday night’s vote of no confidence.