Financial Times FT.com

Making stem cells on demand

By Christine Soares

Published: June 17 2005 16:39 | Last updated: June 17 2005 16:39

Changing muscle into bone and regrowing organs could be the fruits of work on “dedifferentiation”

What can a simple newt do that humans are trying to learn? The tiny amphibian can regenerate an entire lopped-off limb, or a whole organ, by taking normal, differentiated body cells - bone, skin, muscle and so on -and winding back their clocks to an undifferentiated state of stemness. Newts create these instant stem cells at the site of an injury, then immediately begin rebuilding the missing body part.

Stem cell

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