At the Ngwane Park Care Point in Swaziland, children file into a dusty yard to receive an afternoon meal of beans and porridge doled out from large cauldrons by local volunteers. Some are HIV-positive. Many are among the tiny southern African state’s estimated 75,000 Aids orphans, who take home their food to share with brothers, sisters and the grandmother or aunt who has brought them up since their parents’ death.

They are supported by the Global Fund to fight Aids, Tuberculosis and Malaria, an international financing agency that, with nearly $10bn (£5bn, €7.5bn) raised in pledges from donor countries, has helped to transform the battle against the world’s three most lethal infectious diseases.